Research Assistant (CCB/EP)

Job Description

The Systems Genetics group and laboratory led by Assoc. Prof. Enrico Petretto is embedded within the Duke-NUS Centre for Computational Biology. The laboratory has substantial expertise in Systems Biology analysis of various -omics and next-generation sequencing data, and a substantial computational infrastructure to support next-generation sequencing and Big Data analysis. The research focuses on the genetic regulation of complex diseases, including fibrotic heart disease, or kidney disease. For more information, please visit: https://www.duke-nus.edu.sg/cvmd/the-team/primary-appointment/Detail/petretto-enrico-giuseppe 

Selected papers published by the group: 

• WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling (Nature Communications 2019)
• The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis (Nature Communications 2022)

We are looking for a wet-lab Research Assistant, who has experience in performing molecular and cellular experiments to study cardio/pulmonary/kidney and immune-fibrotic traits, with the aim of deciphering the primary genetic factors and regulatory networks underlying cardio-metabolic diseases. The position will be for a period of 2 years, with possibility of renewal depending on the candidate’s work performance and contribution to the project.

The selected candidate will provide expertise in conducting research activities within the overall scope of the research project, including but not limited to the following:

• Perform molecular and cellular biology experiments, including histology procedures, cell/tissue culture, PCR and western blotting.
• Prepare reagents/buffers/solutions/culture medium required for the experiments.
• Contribute to experiment management (including but not limited to planning, organising, conducting, and communicating research studies). 
  • Accurate documentation (i.e. lab log book/notes), reporting and monitoring of experimental results and research findings
  • Evaluate and interpret collected research data / findings and make appropriate recommendations or conclusions.
  • Prepare oral presentations or written reports/scientific manuscripts.
• Contribute to laboratory management (including maintaining lab registries, inventories, safety and ethics, procurement of lab materials and consumables, maintenance of lab equipment) to ensure optimal day to day lab operations.  
• Provide guidance to junior researchers as well as undergraduate and graduate students, and occasional educational/instructional activities.
• Perform other related duties incidental to the work described herein.

Job Requirements

• Bachelor’s / Master’s Degree in a related scientific area (e.g. Life Sciences/Biomedical Sciences) with at least 2 years of relevant work experience. 
• Demonstrated laboratory skills and expertise in supporting various research activities.
• Knowledge of scientific background relevant to the research area.
• Strong team player who is able to prioritise, multi-task and work collaboratively/harmoniously in a diverse workforce. 
• Excellent command of English and communication skills.

We regret that only shortlisted candidates will be notified. 

Covid-19 Message

At NUS, the health and safety of our staff and students are one of our utmost priorities, and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require a significant amount of physical interactions with students/staff/public members. Even for job roles that may be performed remotely, there will be instances where on-campus presence is required.

Taking into consideration the health and well-being of our staff and students and to better protect everyone in the campus, applicants are strongly encouraged to have themselves fully COVID-19 vaccinated to secure successful employment with NUS.

More Information

Location: Outram Campus

Organization: Duke-NUS Medical School

Department : Office of Research

Employee Referral Eligible: No

Job requisition ID : 19056