Research Fellow (OR/CCB/EP)

Job Description

The Systems Genetics group led by Prof. Enrico Petretto is looking for a talented wet-lab Research Fellow to work with a multidisciplinary group of scientists on targeting epithelial WWP2 to ameliorate lung fibrosis. Pulmonary fibrosis interstitial lung diseases (PF-ILDs) have been reported to affect millions of people, posing a substantial burden on individuals, healthcare systems and societies worldwide.  This research project aims to investigate the underlying mechanisms and functional role of a novel E3 ubiquitin ligase, WWP2, discovered by our laboratory, plays in regulation and progression of PF-ILDs. 

The selected candidate will perform a variety of research activities, which include planning, organising and conducting research studies within the overall scope of a research project under the supervision of the Principal Investigator or his/her designate, including but not limited to the following: 

• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Contribute to occasional educational / instructional activities and project management.
• Provide guidance and mentorship to undergraduate / medical students and research assistants.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in a related scientific area (e.g., Life Sciences/Biomedical Sciences, Pharmacology).
• Hands-on experience with transgenic models (breeding and maintenance) and surgery. 
• Experience with rodents (mice/rats) phenotyping, including metabolic traits, biochemistry, histology and microscopy. 
• Hands-on experience with wet-lab techniques in molecular and cell biology, including familiarity with primary cell cultures, iPSC lines, and inflammatory and metabolic cellular assays. 
• Possess knowledge and experience in pharmacology and pharmacokinetics.
• Have a system-level understanding of human cardiometabolic pathology.
• Proven track record in the form of peer-reviewed research publications.
• Demonstrated capability of research independence progressively.
• Possess strong writing and critical thinking skills, as well as good communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.

We regret that only shortlisted candidates will be notified.

More Information

Location: Outram Campus

Organization: Duke-NUS Medical School

Department : Office of Research

Employee Referral Eligible: No

Job requisition ID : 26058