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Research Fellow (OR/NBD/ACC2)

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Date: 16-Oct-2021

Location: Outram Campus, SG

Company: National University of Singapore

Job Description

While the structure and function of the pre-synapse is relatively well-understood, the complex structure attached to the postsynaptic membrane—known as the postsynaptic density—remains largely mysterious. The Human Frontier Science Program has funded a project to study postsynaptic structure and function. This project aims to expand our understanding of the dynamic organization of the postsynaptic scaffold, using a range of methods including proximity labeling, mass spectrometry, and Drosophila neurogenetics.
The Claridge-Chang Lab (www.claridgechang.net) at Duke-NUS Medical School is seeking to appoint a Postdoctoral Research Fellow with a strong background in molecular neuroscience. The collaborative project will involve interactions with a number of other groups, including the Copley, Manser, and Robinson labs. The Fellow will investigate the structure and function of the postsynaptic scaffold.


Job Description
You will work to conduct research activities, including (but not limited to): planning; organising; conducting; and communicating research studies within the overall scope of one or more research projects. Your main duties would include—but are not limited—to the following:
1. To pursue one or more projects using the above-described methods and others as necessary.
2. To learn new methodologies when necessary or useful.
3. Maintain experimental progress.
4. To effectively analyse your results by applying qualitative and quantitative techniques,
5. To conceptualise new ideas and develop plans for independent research.
6. To strive to uphold an excellent standard of statistical graphics.
7. To participate in the education and training of other staff as appropriate.
8. To acquire and maintain knowledge of the literature relevant to the project.
9. To attend appropriate scientific meetings.
10. To stay current with the broader field of neuroscience.
11. To regularly communicate your results to other lab members.
12. To write and review research papers.
13. To work with colleagues on collaborative projects.
14. To contribute to project management,
15. To provide guidance to more junior researchers including students, occasional educational/instructional activities.
16. To share responsibility for the housekeeping of the laboratory area, general maintenance tasks and fly stock maintenance.
17. To conduct scientific sourcing and procurement.
18. To share responsibility with others for laboratory safety.
19. To perform any other duties as may be required from time to time to ensure the efficient running of the laboratory.


Job Requirements

Job Requirements
Candidates must have:
1. A high level of motivation and a keen interest in neuroscience or biochemistry.
2. A PhD or equivalent in a relevant field.
3. Demonstrated knowledge, skills and expertise in neurobiology or biochemistry of neurons (or, in exceptional cases, a related field), with potential to achieve research excellence.
4. Strong publication record or, if recent graduate, high-quality manuscripts.
5. Advanced computer skills for recording, analyzing and organizing data.
6. An ability to work closely with other scientists and an ability to quickly learn new techniques.
7. Excellent communication, teamwork and project management skills. The ability to work harmoniously with a diverse workforce.
8. Experience in scientific sourcing & procurement.
9. Laboratory experimental skills, including the relevant skill set to perform the following techniques: cell culture; transfection methods; molecular biology (subcloning methods including restriction digests, PCR and gel electrophoresis); biochemical analysis; bioinformatic data analysis.
10. Advanced microscopy methods, image analysis (e.g. ImageJ) and neuroanatomical analysis.