Job Description

We are seeking a motivated and technically skilled Research Assistant to join the newly established Yeow Lab at the Cancer Science Institute (CSI), National University of Singapore. This is a unique opportunity to help build a lab from the ground up and play an active role in shaping its team culture

Cell division is fundamental to life, but when dysregulated, it drives cancer. Our lab aims to uncover cancer-specific vulnerabilities within the cell division machinery and translate these insights into new therapeutic strategies. We are also deeply interested in the TRIM family of E3 ubiquitin ligases and how they regulate large protein assemblies involved in mitosis, immune signalling, and protein homeostasis. 

This role is ideal for someone with strong experimental intuition, precision at the bench, and a strong interest in growing into an independent researcher. You will work closely with the Principal Investigator to drive research projects and receive training in advanced techniques such as CRISPR-based genetic screening, live-cell microscopy, and assays to manipulate protein assemblies and degradation pathways.

As a new lab, we are committed to fostering a dynamic, collaborative, and scientifically rigorous environment. We welcome curiosity-driven individuals excited to make foundational discoveries aimed at understanding and combating cancer.

Duties & Responsibilitie

1. Experimental Research Support

•    Design and execute cell and molecular biology experiments, including mammalian cell culture, cloning, immunoblotting.
•    Support the development and optimization of new assays and protocols.
•    Assist with experiments led by other lab members, with training provided where needed.

2. Data Collection & Analysis

•    Collect, organize, and document data using electronic lab notebooks (ELN).

3. Collaborative & Administrative Tasks
•    Collaborate with graduate students, postdoctoral fellows, and collaborators.
•    Contribute to manuscript preparation and the assembly of presentation materials.
•    Maintain lab organization and support the smooth day-to-day operations of the lab.

Qualifications

• Bachelor’s or Master’s degree in the Life Sciences (e.g., Cell Biology, Molecular Biology, Biochemistry, Genetics, or related fields)
• Experience with cell culture, molecular biology techniques, and/or fluorescence microscopy is advantageous
• Demonstrate initiative in learning and applying new techniques, with the opportunity to take ownership of project components over time
• Prior contributions to peer-reviewed publications is desirable
• A passion for biology and an enthusiasm for contributing to CSI’s mission to combat cancer.