About iHealthTech
The Institute for Health Innovation & Technology (iHealthtech) at the National University of Singapore (NUS) is a multidisciplinary research institute dedicated to advancing healthcare through innovation. Bringing together expertise in engineering, medicine, science and technology, iHealthtech develops innovative biomedical technologies and translates research discoveries into practical healthcare solutions. Its research focuses on areas such as biomedical devices, diagnostics, digital health, artificial intelligence, biosensors, microfluidics and personalised medicine. Through close collaborations with clinicians, industry partners and healthcare institutions, iHealthtech aims to bridge the gap between scientific discovery and clinical application, fostering innovations that improve healthcare outcomes and benefit society.
Job Description
We are inviting applications for a Postdoctoral Fellow/Research Fellow position to join our dynamic and interdisciplinary team focused on developing electrochemical sensing technologies for early and accurate disease detection. The successful candidate will work at the interface of micro/nanofabrication, point-of-care (POC) development, and biomedical diagnostics.
This role offers a unique opportunity to contribute to the design and optimization of integrated sensing platforms for detecting clinically relevant biomarkers such as cardiac-related biomarkers.
Key Responsibilities
- Conduct independent and collaborative research in electrochemical biosensing.
- Perform micro/nanofabrication and surface modification for developing high-sensitivity electrochemical sensors.
- Design and optimize sensor platforms for specific disease applications, including cardiovascular disease.
- Develop and optimize electrochemical electrochemical sensor assays in plasma, focusing on matrix robustness (fouling, interference, stability) and multiplex compatibility.
- Plan experiments, collect and analyze data using appropriate analytical tools and software.
- Work with interdisciplinary teams including clinicians to integrate sensors with complementary technologies, such as microfluidics or wearable platforms.
- Prepare research publications, technical reports, and conference presentations.
- Keep abreast of emerging developments in electrochemical sensing, diagnostics, and biomedical engineering.
The successful candidate will be offered a full time (contract) as a member of the laboratory.
Qualifications
- Ph.D. in Biomedical Engineering, Chemistry, Electrical Engineering, Materials Science, or a related discipline.
- Demonstrated hands‑on experience with electrochemical biosensors, surface functionalization in complex biological matrices, microfluidics and analytical chemistry.
- Strong analytical skills and experience with signal processing or data analysis tools.
- Excellent communication skills and the ability to work in a multidisciplinary team.
- Experience developing aptamers (e.g., SELEX), or substantial experience integrating affinity reagents into electrochemical platforms.
- Experience with multiplex assay development and cross‑reactivity management.
Preferred Skills
- Experience in aptamer selection, modification, and structure-switching probe design.
- Hands-on electrochemical techniques (DPV, SWV, CV, EIS) for biosensor characterization.
- Surface functionalization of gold or carbon electrodes (thiol chemistry, SAMs, nanomaterials).
- Micro/nanofabrication techniques, such as photolithography, electrodeposition, or screen-printing.
- Bioassay development in complex matrices (plasma, serum, whole blood).
- Familiarity with signal optimization, noise reduction, and calibration strategies for POC sensing.
- Knowledge of device packaging and system integration is a plus.
To apply, please send your cover letter, CV and names of 3 references (name, institution, email). We regret to inform you that only shortlisted candidates will be contacted.