Job Description

The Research Pathologist will provide expert pathology input to support and advance translational research within the Experimental Therapeutics Program, with a primary focus on solid tumors, particularly breast cancer and nasopharyngeal cancer. The role is integral to bridging clinical pathology with laboratory-based discovery, biomarker development, and therapeutic innovation, contributing to precision oncology and investigator-initiated clinical trials.

Research Support and Pathology Expertise

• Perform detailed analysis and interpretation of morphological features of human clinical specimens for research purposes.
• Provide expert scoring and interpretation of histological and molecular pathology assays, including immunohistochemistry (IHC), in situ hybridization (ISH), and fluorescence in situ hybridization (FISH).
• Correlate pathological findings with molecular, genomic, and clinical data to support biomarker discovery and validation.
• Lead the development, optimization, and validation of pathology-based research platforms, including but not limited to:
  • Immunohistochemistry (IHC) assays
  • Construction and utilization of tissue microarrays (TMAs)
  • Laser capture microdissection (LCM)
  • Automated staining platforms (autostainers)
  • Digital slide scanning and imaging systems
  • Advanced light, fluorescence, and confocal microscopy systems
  • Ensure quality control, standardization, and reproducibility of pathology workflows in compliance with research and institutional standards.

Project Leadership and Scientific Contribution

• Provide scientific leadership for pathology-driven and pathology-enabled research projects within the laboratory and across collaborative programs.
• Contribute pathology expertise to translational studies involving novel therapeutics, predictive biomarkers, liquid biopsy–correlated tissue analyses, and pharmacogenetic research.
• Support clinical trial–related pathology activities, including biomarker-driven patient stratification and correlative studies.

Supervision, Training, and Mentorship

• Supervise, mentor, and train junior research staff, students, and fellows in histopathology techniques, assay interpretation, and good laboratory practices.
• Foster a culture of scientific rigor, critical thinking, and continuous learning within the pathology component of the program.

Scientific Communication and Grants

• Assist in the preparation, review, and compilation of manuscripts, abstracts, reports, and grant applications.
• Contribute to data interpretation, figure preparation, and pathology-related sections of scientific publications and funding proposals.

Collaboration and Stakeholder Engagement

• Work closely with clinicians, molecular biologists, bioinformaticians, and clinical trial teams in a multidisciplinary research environment.
• Provide pathology consultation and input to internal and external collaborators as required.

Requirements

Essential Qualifications

• MBBS or MD degree.

Preferred Experience and Skills

• Several years of experience as a diagnostic histopathologist or surgical pathologist.
• Hands-on experience in one or more of the following:
  • Immunohistochemistry (IHC)
  • Laser capture microdissection
  • Construction and analysis of tissue microarrays
  • Diagnostic molecular pathology or molecular biology techniques
• Strong understanding of disease pathogenesis and pathological processes at the tissue and cellular level.

Competencies and Attributes

• Ability to work independently with minimal supervision while managing multiple projects.
• Excellent written and spoken English communication skills.
• Strong scientific writing, reporting, and data interpretation capabilities.
• Demonstrated collaborative mindset and ability to work effectively in multidisciplinary and translational research teams.
• High level of professionalism, attention to detail, and commitment to research integrity.