Job Description

The Neurobiology Research Programme at the Life Sciences Institute (LSI), National University of Singapore, invites applications for a Research Assistant to support research on the molecular mechanisms underlying human neurodegenerative diseases. The successful candidate will join a multidisciplinary research environment led by Professor Rickie Patani, focusing on understanding the cellular and molecular drivers of neurodegeneration and the biology of RNA processing in neurological disease.

Key Responsibilities

• Conduct molecular and cellular biology experiments investigating mechanisms of neurodegeneration.
• Assist in studies examining RNA processing mechanisms, including intron retention, in neuronal health and disease.
• Perform experiments using human stem cell-derived neuronal models and other cellular systems.
• Support experimental work related to neuronal cell biology, including cell culture, molecular assays, and imaging.
• Assist with the development and maintenance of experimental models relevant to neurodegenerative diseases.
• Collect, analyze, and interpret experimental data using appropriate statistical and bioinformatics tools.
• Maintain accurate laboratory records and ensure compliance with laboratory safety and research protocols.
• Contribute to preparation of research reports, publications, and grant applications.
• Assist in general laboratory management, including ordering reagents, maintaining equipment, and coordinating shared resources.
• Collaborate with researchers across the Neurobiology Programme and affiliated research groups within NUS.

Qualifications

• Bachelor’s degree in Neuroscience, Molecular Biology, Life Sciences, Biochemistry, or related disciplines.
• Prior laboratory experience in molecular or cellular biology techniques is preferred.
• Experience in any of the following areas will be advantageous:
  1. RNA biology or transcriptomics
  2. Stem cell culture or neuronal differentiation
  3. Neurodegenerative disease models
  4. Imaging or bioinformatics analysis
• Strong organizational and analytical skills with attention to detail.
• Ability to work both independently and collaboratively in a multidisciplinary research environment.
• Good communication skills and willingness to contribute to scientific publications.