Job Description
The National University of Singapore invites applications for Research Assistant (Production Radiochemist) in the Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine. CIRC is a dedicated molecular imaging research centre. It is equipped with on-site capability for the preparation of PET radiopharmaceuticals in a state-of-the-art GMP-certified facility. CIRC is positioned to support both academic and commercially led clinical research programs, with dedicated clinical imaging facilities area advanced modalities of PET-CT and PET-MRI. For more details on what we do, do visit https://medicine.nus.edu.sg/circ/. Appointments will be made on a two-years contract basis with the possibility of extension.
Purpose of the post
The Production Radiochemist at Clinical Imaging Research Centre (CIRC) is responsible for the routine production of radiopharmaceuticals inside the Clean Room environment, in compliance with Good Manufacturing Practice (GMP). The Radiochemist will be assisting in the method development and validation of new radiopharmaceuticals, including the preparation of standard operating procedures (SOPs) and other quality documentation. With strong technical and analytical expertise, the Production Radiochemist helps maintain high operational uptime, ensures regulatory compliance, and upholds patient and product safety standards.
Main duties and responsibilities
The Production Radiochemist will be able to:
1. Perform radiolabelling of peptides, antibodies, or small molecules using radionuclides such as Lu-177, Ga-68, F-18, etc.
2. Prepare and review batch records, lab notebooks, SOPs and other QC documents.
3. Assist with emergency maintenance/calibration of radiochemistry synthesis and dispensing modules (e.g., Scintomics, iPhase, Trasis).
4. Support deviation investigations, CAPAs, and change control implementations as needed.
5. Perform ad-hoc clean room activities, including cleaning of rooms, stock inventory and environmental monitoring.
6. Safe handling of radioactive materials including hazardous waste disposal.
7. Working flexible hours, shifts, or weekends based on production schedules and isotope half-lives.
8. Performing any other duties as assigned by the Head of Department in accordance with GMP and safety regulations.
Physical Demands and Work Environment
Personnel should be:
• Willing to work with radioactive materials
• Able to read, listen and understand technical direction and procedures
• Able to lift heavy loads (up to 14kg with both hands)
Qualifications
The applicant should:
- Have a minimum of BSc degree in Synthetic Organic/ Inorganic/ Medical Chemistry or a related science discipline;
- Practical experiences in general laboratory techniques, such as analytical balance operations, pipetting, pH measurement and reagents preparation.
- Experiences in pharmaceutical production under Good Manufacturing Practice (GMP) is an added advantage.
- Experiences in radiolabelling and purification techniques with short-lived radioisotopes (F-18, C-11, Ga-68) or Lu-177 is highly desirable.
- Proven ability to work independently with minimum supervision as well as a constructive team player.
- Require critical thinking and problem-solving skills
- High attention to detail and commitment to data integrity.
- Fresh graduate with relevant academic and skills will be considered for this position
- Ability to perform first-line troubleshooting and minor repairs on automated modules (e.g., replacing tubing, valves, connectors, heaters).
- Ability to read technical manuals, interpret wiring diagrams, and communicate effectively with engineers or vendors for equipment servicing.
Remuneration will be commensurate with the candidate’s qualifications and experience. Informal enquiries are welcome and should be made to Miss Emmalyn Chan Mei Mei at emma.chan@nus.edu.sg.
Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of three (3) referees to this job portal.
We regret that only shortlisted candidates will be notified.
More Information
Location: Kent Ridge Campus
Organization: Yong Loo Lin School of Medicine
Department : Dean-Med-Clinical Imaging Research Centre
Employee Referral Eligible: No
Job requisition ID : 29712