Job Description

The successful candidate will work with PIs Associate Professor Duane Loh and Assistant Professor Tan Yongzi on computational phase retrieval for cryo-electron microscopy of floppy, low-contrast RNA molecules.

The main responsibilities of the position include:

1. Develop realistic forward model to simulate noisy cryo-electron micrographs from RNA biomolecules.
2. Perform computational phase retrieval on 2D micrographs using physics-informed neural networks.
3. Infer structural variability of floppy biomolecules from computationally phase-retrieved micrographs.

Qualifications

Ph.D. in physics-related disciplines.

Experience:

• Fluent in high-performance scientific computing and imaging in python, and comfortable in the Unix environment.

Skills:

• Strong foundation in computational optics, deep learning, high performance computing, and structural biology in cryo-EM

More Information

Location: Kent Ridge Campus

Organization: Science

Department : Biological Sciences

Employee Referral Eligible: No

Job requisition ID : 26264