Job Description
The Mechanobiology Institute (MBI) at the National University of Singapore (NUS) is a leading multi-disciplinary institute devoted to developing new paradigms for understanding biological functions in health and diseases from the perspective of cell, tissue and organ mechanics/dynamics and mechano-signal transduction. The institute operates on a fully integrated open-lab philosophy, with an extensive infrastructure supported by core facilities dedicated to technology such as state-of-the-art light microscopy, nano- and micro- fabrication, and computing.
We are seeking a highly motivated Research Fellow with strong expertise in electron microscopy (EM) to join our multidisciplinary team. The successful candidate will lead EM-based investigations and contribute to the development of advanced imaging protocols. This position offers access to cutting-edge electron and light microscopy platforms, with opportunities to engage in collaborative biomedical research of high impact. This role requires a solid background in biomedical or life sciences research. Applications without relevant experience in biological sample preparation and imaging will not be considered.
Key Responsibilities
- Develop, optimize, and execute protocols for the preparation of biological samples for EM, including fixation, staining, embedding, sectioning, and mounting
- Operate and maintain high-resolution electron microscopes, ensuring reliable imaging and data quality
- Design and conduct imaging workflows tailored to specific biomedical research questions, including data acquisition, interpretation, and troubleshooting
- Document protocols, imaging parameters, and results in a systematic and reproducible manner
- Collaborate with life science researchers to integrate EM into broader experimental designs and contribute to scientific publications and grant applications
- Support complementary light microscopy techniques when relevant; training will be provided if needed
- Provide technical guidance or mentorship to junior researchers, including supervision of EM sample preparation and imaging procedures
Qualifications
- PhD in a relevant field such as Cell Biology, Biomedical Sciences, Biophysics, or related life sciences
- Demonstrated hands-on experience in biological electron microscopy, particularly in the preparation and imaging of biological specimens
- Familiarity with biological ultrastructure and experience interpreting EM data in a biomedical context
- Strong technical knowledge of EM instrumentation and sample processing workflows
- Ability to work independently, manage multiple projects, and contribute actively to collaborative research
- Excellent organizational skills and attention to detail, with a commitment to scientific rigor and reproducibility
- Proven track record of scientific output (e.g. publications, presentations)
- (Preferred) Prior experience in a core imaging facility or collaborative research environment
- (Preferred) Experience with light microscopy imaging and correlative workflows (CLEM) will be advantageous
- (Preferred) Familiarity with image analysis tools and quantitative data processing for microscopy
- (Preferred) Demonstrated ability to mentor or train junior staff or students
To Apply
Applications should include:
- a detailed curriculum vitae including a list of publications
- a cover letter outlining relevant experience in biomedical research and electron microscopy
- the contact details for two to three professional references
Specific inquiries about this position can be sent via email to Dr. Beghin at mbianne@nus.edu.sg. We regret that only shortlisted candidates will be notified.
More Information
Location: Kent Ridge Campus
Organization: Mechanobiology Institute
Department : Research
Employee Referral Eligible: No
Job requisition ID : 28591